EMD-42018

Single-particle
3.3 Å
EMD-42018
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Deposition: 16/09/2023
Map released: 10/01/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42018
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8u89 summary report (pdf.gz) Map and 8u89 FULL report (pdf.gz)
EMICSS annotations (xml)

The structure of the PP2A-B56Delta holoenzyme mutant - E197K

EMD-42018

Single-particle
3.3 Å
EMD-42018
3D View Gallery
Deposition: 16/09/2023
Map released: 10/01/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Protein Phosphatase 2A B56 Delta holoenzyme mutant - E197K
Fitted models: 8u89

Deposition Authors: Wu CG , Xing Y
B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations.
Wu CG , Balakrishnan VK, Merrill RA, Parihar PS , Konovolov K, Chen YC, Xu Z , Wei H , Sundaresan R, Cui Q , Wadzinski BE , Swingle MR, Musiyenko A , Chung WK , Honkanen RE , Suzuki A , Huang X , Strack S , Xing Y
(2024) PNAS , 121 , e2310727120 - e2310727120
PUBMED: 38150499
DOI: doi:10.1073/pnas.2310727120
ISSN: 1091-6490
ASTM: PNASA6