Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-41898
(N3Occluded Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
EMD-41898
Single-particle3.43 Å
Deposition: 11/09/2023Map released: 16/10/2024
Last modified: 16/10/2024
Sample Organism:
Homo sapiens
Sample: cystic fibrosis transmembrane conductance regulator(CFTR)
Deposition Authors: Wang C
,
Singh S
,
Loughlin BJ,
Yang Z,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Rich Z,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Hunt JF
,
Cohen BM
Sample: cystic fibrosis transmembrane conductance regulator(CFTR)
Deposition Authors: Wang C
,
Singh S
,
Loughlin BJ,
Yang Z,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Rich Z,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Hunt JF
,
Cohen BM
(N3 Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Wang C
,
Singh S
,
Loughlin BJ,
Yang Z,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Rich Z,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Hunt JF
,
Cohen BM
To Be Published
,
Singh S
,
Loughlin BJ,
Yang Z,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Rich Z,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Hunt JF
,
Cohen BM
To Be Published
Grant Support:
- Cystic Fibrosis Foundation: Hunt18G0 (United States)
- Cystic Fibrosis Foundation: Hunt20G0 (United States)
- Cystic Fibrosis Foundation: HUNT13XX0 (United States)
- Cystic Fibrosis Foundation: 004400G222 (United States)
- Cystic Fibrosis Foundation: FRANK16XX0 (United States)
- Cystic Fibrosis Foundation: FRANK18G0 (United States)
