EMD-41838
Cryo-EM structure of vaccine-elicited CD4 binding site antibody DH1285 bound to partially open HIV-1 CH505TFchim.6R.SOSIP.664v4.1 Env
EMD-41838
Single-particle6.78 Å
Deposition: 05/09/2023Map released: 03/01/2024
Last modified: 17/07/2024
Sample Organism:
Human immunodeficiency virus 1
Sample: A Complex of ectodomain of HIV-1 CH505TFchim.6R.SOSIP.664v4.1 Env with CD4 binding site antibody Dh1285 Fab in 1:3 ratio
Deposition Authors: Thakur B
,
Stalls VD ,
Acharya P
Sample: A Complex of ectodomain of HIV-1 CH505TFchim.6R.SOSIP.664v4.1 Env with CD4 binding site antibody Dh1285 Fab in 1:3 ratio
Deposition Authors: Thakur B
,
Stalls VD ,
Acharya P
Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques.
Saunders KO,
Counts J,
Thakur B ,
Stalls V,
Edwards R,
Manne K,
Lu X,
Mansouri K,
Chen Y,
Parks R,
Barr M,
Sutherland L,
Bal J,
Havill N,
Chen H,
Machiele E,
Jamieson N ,
Hora B,
Kopp M,
Janowska K,
Anasti K,
Jiang C,
Van Itallie E,
Venkatayogi S,
Eaton A,
Henderson R ,
Barbosa C,
Alam SM,
Santra S,
Weissman D,
Moody MA,
Cain DW,
Tam YK,
Lewis M,
Williams WB,
Wiehe K,
Montefiori DC,
Acharya P ,
Haynes BF
(2024) Cell , 187 , 79 - 94.e24
,
Stalls V,
Edwards R,
Manne K,
Lu X,
Mansouri K,
Chen Y,
Parks R,
Barr M,
Sutherland L,
Bal J,
Havill N,
Chen H,
Machiele E,
Jamieson N ,
Hora B,
Kopp M,
Janowska K,
Anasti K,
Jiang C,
Van Itallie E,
Venkatayogi S,
Eaton A,
Henderson R ,
Barbosa C,
Alam SM,
Santra S,
Weissman D,
Moody MA,
Cain DW,
Tam YK,
Lewis M,
Williams WB,
Wiehe K,
Montefiori DC,
Acharya P ,
Haynes BF
(2024) Cell , 187 , 79 - 94.e24