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EMD-41838
Cryo-EM structure of vaccine-elicited CD4 binding site antibody DH1285 bound to partially open HIV-1 CH505TFchim.6R.SOSIP.664v4.1 Env
EMD-41838
Single-particle6.78 Å
Deposition: 05/09/2023Map released: 03/01/2024
Last modified: 17/07/2024
Sample Organism:
Human immunodeficiency virus 1
Sample: A Complex of ectodomain of HIV-1 CH505TFchim.6R.SOSIP.664v4.1 Env with CD4 binding site antibody Dh1285 Fab in 1:3 ratio
Deposition Authors: Thakur B
,
Stalls VD ,
Acharya P
Sample: A Complex of ectodomain of HIV-1 CH505TFchim.6R.SOSIP.664v4.1 Env with CD4 binding site antibody Dh1285 Fab in 1:3 ratio
Deposition Authors: Thakur B
,
Stalls VD ,
Acharya P
Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques.
Saunders KO,
Counts J,
Thakur B ,
Stalls V,
Edwards R,
Manne K,
Lu X,
Mansouri K,
Chen Y,
Parks R,
Barr M,
Sutherland L,
Bal J,
Havill N,
Chen H,
Machiele E,
Jamieson N ,
Hora B,
Kopp M,
Janowska K,
Anasti K,
Jiang C,
Van Itallie E,
Venkatayogi S,
Eaton A,
Henderson R,
Barbosa C,
Alam SM,
Santra S,
Weissman D,
Moody MA,
Cain DW,
Tam YK,
Lewis M,
Williams WB,
Wiehe K,
Montefiori DC,
Acharya P ,
Haynes BF
(2024) Cell , 187 , 79 - 94.e24
,
Stalls V,
Edwards R,
Manne K,
Lu X,
Mansouri K,
Chen Y,
Parks R,
Barr M,
Sutherland L,
Bal J,
Havill N,
Chen H,
Machiele E,
Jamieson N ,
Hora B,
Kopp M,
Janowska K,
Anasti K,
Jiang C,
Van Itallie E,
Venkatayogi S,
Eaton A,
Henderson R,
Barbosa C,
Alam SM,
Santra S,
Weissman D,
Moody MA,
Cain DW,
Tam YK,
Lewis M,
Williams WB,
Wiehe K,
Montefiori DC,
Acharya P ,
Haynes BF
(2024) Cell , 187 , 79 - 94.e24