EMD-41831
Gradient-fixed lipidated recombinant apolipoprotein E4
EMD-41831
Single-particle7.71 Å
Deposition: 03/09/2023Map released: 24/01/2024
Last modified: 17/04/2024
Sample Organism:
Escherichia coli
Sample: Gradient fixed lipidated recombinant apolipoprotein E4 in complex with monoclonal anti-ApoE F(ab')2 fragment
Deposition Authors: Strickland MR
,
Rau M,
Summers B,
Basore K,
Wulf II J,
Jiang H,
Chen Y,
Ulrich JD,
Randolph GJ,
Zhang R ,
Fitzpatrick JAJ,
Cashikar AG ,
Holtzman DM
Sample: Gradient fixed lipidated recombinant apolipoprotein E4 in complex with monoclonal anti-ApoE F(ab')2 fragment
Deposition Authors: Strickland MR
,
Rau M,
Summers B,
Basore K,
Wulf II J,
Jiang H,
Chen Y,
Ulrich JD,
Randolph GJ,
Zhang R ,
Fitzpatrick JAJ,
Cashikar AG ,
Holtzman DM
Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins.
Strickland MR ,
Rau MJ,
Summers B,
Basore K,
Wulf 2nd J,
Jiang H,
Chen Y,
Ulrich JD,
Randolph GJ,
Zhang R ,
Fitzpatrick JAJ,
Cashikar AG ,
Holtzman DM
(2024) Neuron , 112 , 1100 - 1109.e5
,
Rau MJ,
Summers B,
Basore K,
Wulf 2nd J,
Jiang H,
Chen Y,
Ulrich JD,
Randolph GJ,
Zhang R ,
Fitzpatrick JAJ,
Cashikar AG ,
Holtzman DM
(2024) Neuron , 112 , 1100 - 1109.e5
Grant Support:
- National Institutes of Health/National Institute on Aging (NIH/NIA): T32AG058518 (United States)
- National Institutes of Health/National Institute on Aging (NIH/NIA): RF1NS090934 (United States)
- National Institutes of Health/National Institute on Aging (NIH/NIA): 1U19AG069701 (United States)
- National Science Foundation (NSF, United States): DGE-1745038 (United States)
- Other private: (United States)