EMD-41572

Single-particle
2.53 Å
EMD-41572
3D View Gallery
Deposition: 09/08/2023
Map released: 16/10/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41572

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8tr7 summary report (pdf.gz) Map-8tr7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the rat P2X7 receptor in complex with the allosteric antagonist A839977

EMD-41572

Single-particle
2.53 Å
EMD-41572
3D View Gallery
Deposition: 09/08/2023
Map released: 16/10/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus
Sample: Membrane protein
Fitted models: 8tr7

Deposition Authors: Oken AC , Ditter IA , Lisi NE , Krishnamurthy I , McCarthy AE, Godsey MH , Mansoor SE
P2X 7 receptors exhibit at least three modes of allosteric antagonism.
Oken AC , Ditter IA , Lisi NE , Krishnamurthy I , Godsey MH , Mansoor SE
(2024) Sci Adv , 10 , eado5084 - eado5084
PUBMED: 39365862
DOI: doi:10.1126/sciadv.ado5084
ISSN: 2375-2548