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EMD-41440
Cryo-EM structure of TRNM-f*01 Fab in complex with HIV-1 Env trimer ConC SOSIP
EMD-41440
Single-particle4.03 Å
Deposition: 03/08/2023Map released: 07/08/2024
Last modified: 14/05/2025
Sample Organism:
Macaca mulatta,
Homo sapiens
Sample: TRNM-f*01 Fab in complex with HIV-1 Env trimer ConC SOSIP
Fitted models: 8to9
Deposition Authors: Roark RS, Morano NC, Shapiro LS, Kwong PD
Sample: TRNM-f*01 Fab in complex with HIV-1 Env trimer ConC SOSIP
Fitted models: 8to9
Deposition Authors: Roark RS, Morano NC, Shapiro LS, Kwong PD
Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Wang H,
Cheng C,
Dal Santo JL,
Shen CH,
Bylund T ,
Henry AR,
Howe CA,
Hwang J,
Morano NC,
Morris DJ ,
Pletnev S,
Roark RS,
Zhou T,
Hansen BT,
Hoyt FH,
Johnston TS,
Wang S,
Zhang B,
Ambrozak DR,
Becker JE,
Bender MF,
Changela A,
Chaudhary R,
Corcoran M,
Corrigan AR,
Foulds KE,
Guo Y ,
Lee M,
Li Y,
Lin BC,
Liu T,
Louder MK,
Mandolesi M,
Mason RD,
McKee K,
Nair V,
O'Dell S,
Olia AS,
Ou L,
Pegu A,
Raju N,
Rawi R,
Roberts-Torres J,
Sarfo EK,
Sastry M,
Schaub AJ,
Schmidt SD,
Schramm CA,
Schwartz CL ,
Smith SC,
Stephens T,
Stuckey J,
Teng IT,
Todd JP,
Tsybovsky Y,
Van Wazer DJ,
Wang S,
Doria-Rose NA,
Fischer ER,
Georgiev IS,
Karlsson Hedestam GB,
Sheng Z,
Woodward RA,
Douek DC,
Koup RA,
Pierson TC,
Shapiro L,
Shaw GM,
Mascola JR,
Kwong PD
(2024) Cell , 187 , 7214 - 7231.e23
,
Henry AR,
Howe CA,
Hwang J,
Morano NC,
Morris DJ ,
Pletnev S,
Roark RS,
Zhou T,
Hansen BT,
Hoyt FH,
Johnston TS,
Wang S,
Zhang B,
Ambrozak DR,
Becker JE,
Bender MF,
Changela A,
Chaudhary R,
Corcoran M,
Corrigan AR,
Foulds KE,
Guo Y ,
Lee M,
Li Y,
Lin BC,
Liu T,
Louder MK,
Mandolesi M,
Mason RD,
McKee K,
Nair V,
O'Dell S,
Olia AS,
Ou L,
Pegu A,
Raju N,
Rawi R,
Roberts-Torres J,
Sarfo EK,
Sastry M,
Schaub AJ,
Schmidt SD,
Schramm CA,
Schwartz CL ,
Smith SC,
Stephens T,
Stuckey J,
Teng IT,
Todd JP,
Tsybovsky Y,
Van Wazer DJ,
Wang S,
Doria-Rose NA,
Fischer ER,
Georgiev IS,
Karlsson Hedestam GB,
Sheng Z,
Woodward RA,
Douek DC,
Koup RA,
Pierson TC,
Shapiro L,
Shaw GM,
Mascola JR,
Kwong PD
(2024) Cell , 187 , 7214 - 7231.e23
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