EMDB < EMD-4141

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

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perform basic research in molecular biology

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offer vital services to scientists in the member states

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scientists, students and visitors at all levels

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and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

EMD-4141

Single-particle
6.7 Å

EMD-4141

3D View Gallery

Deposition: 10/10/2016
Map released: 18/01/2017
Last modified: 13/11/2024

Overview 3D View Sample Experiment Validation Additional data Links

Overview 3D View Sample Experiment Validation Additional data Links

EMD-4141

Download

Cryo-EM structure of the E. coli replicative DNA polymerase-clamp-exonuclase-theta complex bound to DNA in the editing mode

EMD-4141

Single-particle
6.7 Å
EMD-4141

EMD-4141

3D View Gallery

Deposition: 10/10/2016
Map released: 18/01/2017
Last modified: 13/11/2024

Overview 3D View Sample Experiment Validation Additional data Links

Sample Organism: Escherichia coli K12, synthetic construct
Sample: DNA polymerase III alpha, beta, epsilon, theta complex with mismatched DNA duplex
Fitted models: 5m1s

Deposition Authors: Fernandez-Leiro R , Conrad J

Self-correcting mismatches during high-fidelity DNA replication.

Fernandez-Leiro R , Conrad J, Yang JC, Freund SM, Scheres SH, Lamers MH
(2017) Nat Struct Mol Biol , 24 , 140 - 143

PUBMED: 28067916
DOI: doi:10.1038/nsmb.3348
ISSN: 1545-9985