EMD-41126

Single-particle
2.74 Å
EMD-41126
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Deposition: 26/06/2023
Map released: 31/01/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41126
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8ta2 summary report (pdf.gz) Map and 8ta2 FULL report (pdf.gz)
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Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with bound inhibitor AK-42

EMD-41126

Single-particle
2.74 Å
EMD-41126
3D View Gallery
Deposition: 26/06/2023
Map released: 31/01/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Chloride channel protein 2 with inhibitor AK-42
Fitted models: 8ta2

Deposition Authors: Xu M , Neelands T, Powers AS, Liu Y , Miller S, Pintilie G, Du Bois J, Dror RO , Chiu W , Maduke M
CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Xu M , Neelands T, Powers AS, Liu Y , Miller SD, Pintilie GD, Bois JD, Dror RO , Chiu W , Maduke M
(2024) eLife , 12
PUBMED: 38345841
DOI: doi:10.7554/eLife.90648
ISSN: 2050-084X