EMD-41072

Single-particle
3.14 Å
EMD-41072
3D View Gallery
Deposition: 16/06/2023
Map released: 25/12/2024
Last modified: 14/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41072
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8t6m summary report (pdf.gz) Map and 8t6m FULL report (pdf.gz)
EMICSS annotations (xml)

Human leukocyte antigen bound by two alloreactive antibody Fabs

EMD-41072

Single-particle
3.14 Å
EMD-41072
3D View Gallery
Deposition: 16/06/2023
Map released: 25/12/2024
Last modified: 14/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: L02/M07/A*01:01 complex
Fitted models: 8t6m

Deposition Authors: Kizziah JL, Killian JT, Diaz-Avalos R, Qiu S, Yang G, Green T, Lund FE
Topography of the HLA-A protein enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients.
Killian Jr JT, King RG, Lucander ACK, Kizziah JL, Fucile CF, Diaz-Avalos R, Qiu S, Silva-Sanchez A, Mousseau BJ, Macon KJ, Callahan AR, Yang G, Hossain ME, Akther J, Good DB, Kelso S, Houp JA, Rosenblum F, Porrett PM, Ong SC, Kumar V, Saphire EO, Kearney JF, Randall TD, Rosenberg AF, Green TJ, Lund FE
(2025) Immunity , 58 , 3040 - 3060.e12
PUBMED: 41289995
DOI: doi:10.1016/j.immuni.2025.10.014
ISSN: 1074-7613
ASTM: IUNIEH