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EMD-41071

Single-particle
3.3 Å
EMD-41071
3D View Gallery
Deposition: 16/06/2023
Map released: 06/03/2024
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41071
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8t6l summary report (pdf.gz) Map and 8t6l FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of rat cardiac sodium channel NaV1.5 with batrachotoxin analog BTX-B

EMD-41071

Single-particle
3.3 Å
EMD-41071
3D View Gallery
Deposition: 16/06/2023
Map released: 06/03/2024
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus, Aequorea victoria
Sample: Sodium channel NaV1.5 and batrachotoxinin-A 20-alpha-benzoate
Fitted models: 8t6l

Deposition Authors: Tonggu L , Wisedchaisri G , Gamal El-Din TM , Zheng N , Catterall WA
Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin.
Tonggu L , Wisedchaisri G , Gamal El-Din TM , Lenaeus MJ, Logan MM, Toma T, Du Bois J , Zheng N , Catterall WA
(2024) Nat Commun , 15 , 2306 - 2306
PUBMED: 38485923
DOI: doi:10.1038/s41467-024-45958-w
ISSN: 2041-1723