EMD-40789
BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
EMD-40789
Single-particle3.2 Å
Deposition: 16/05/2023Map released: 30/08/2023
Last modified: 27/11/2024
Sample Organism:
Homo sapiens,
Xenopus laevis,
synthetic construct
Sample: BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
Fitted models: 8svf
Deposition Authors: Thomas JF, Valencia-Sanchez MI
,
Armache K-J
Sample: BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
Fitted models: 8svf
Deposition Authors: Thomas JF, Valencia-Sanchez MI
,
Armache K-J
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1.
Thomas JF,
Valencia-Sanchez MI ,
Tamburri S ,
Gloor SL ,
Rustichelli S ,
Godinez-Lopez V,
De Ioannes P ,
Lee R ,
Abini-Agbomson S ,
Gretarsson K ,
Burg JM,
Hickman AR ,
Sun L ,
Gopinath S,
Taylor HF ,
Sun ZW,
Ezell RJ,
Vaidya A,
Meiners MJ ,
Cheek MA,
Rice WJ ,
Svetlov V ,
Nudler E ,
Lu C ,
Keogh MC ,
Pasini D ,
Armache KJ
(2023) Sci Adv , 9 , eadg9832 - eadg9832
,
Tamburri S ,
Gloor SL ,
Rustichelli S ,
Godinez-Lopez V,
De Ioannes P ,
Lee R ,
Abini-Agbomson S ,
Gretarsson K ,
Burg JM,
Hickman AR ,
Sun L ,
Gopinath S,
Taylor HF ,
Sun ZW,
Ezell RJ,
Vaidya A,
Meiners MJ ,
Cheek MA,
Rice WJ ,
Svetlov V ,
Nudler E ,
Lu C ,
Keogh MC ,
Pasini D ,
Armache KJ
(2023) Sci Adv , 9 , eadg9832 - eadg9832
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM115882 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): R01CA266978 (United States)
- The Mark Foundation: (United States)