EMD-40756

Single-particle
2.93 Å
EMD-40756
3D View Gallery
Deposition: 09/05/2023
Map released: 07/02/2024
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40756

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8st3 summary report (pdf.gz) Map-8st3 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The 2alpha3beta stoichiometry of human alpha4beta2 nicotinic acetylcholine receptor in complex with acetylcholine and calcium

EMD-40756

Single-particle
2.93 Å
EMD-40756
3D View Gallery
Deposition: 09/05/2023
Map released: 07/02/2024
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: A complex of three Fab fragments with the 2alpha3beta stoichiometry of human alpha4beta2 nicotinic receptor bound to acetylcholine and calcium
Fitted models: 8st3

Deposition Authors: Kang G , Hibbs RE
Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor.
Mazzaferro S , Kang G , Natarajan K , Hibbs RE , Sine SM
(2024) Br.J.Pharmacol. , 181 , 1973 - 1992
PUBMED: 38454578
DOI: doi:10.1111/bph.16321
ISSN: 0007-1188
ASTM: BJPCBH