EMD-40480
TUBB4B and TUBA1A Heterodimer from Human Respiratory Doublet Microtubules
EMD-40480
Single-particle2.8 Å
Deposition: 13/04/2023Map released: 01/05/2024
Last modified: 20/11/2024
Sample Organism:
Homo sapiens
Sample: TUBB4B and TUBA1A Heterodimer from Human Respiratory Doublet Microtubules
Fitted models: 8sh7
Deposition Authors: Anderson JR
,
Gui M,
Brown A
Sample: TUBB4B and TUBA1A Heterodimer from Human Respiratory Doublet Microtubules
Fitted models: 8sh7
Deposition Authors: Anderson JR
,
Gui M,
Brown A
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules.
Dodd DO
,
Mechaussier S
,
Yeyati PL
,
McPhie F
,
Anderson JR
,
Khoo CJ
,
Shoemark A
,
Gupta DK
,
Attard T,
Zariwala MA
,
Legendre M
,
Bracht D
,
Wallmeier J
,
Gui M,
Fassad MR
,
Parry DA
,
Tennant PA
,
Meynert A
,
Wheway G
,
Fares-Taie L
,
Black HA
,
Mitri-Frangieh R,
Faucon C,
Kaplan J,
Patel M
,
McKie L
,
Megaw R
,
Gatsogiannis C,
Mohamed MA,
Aitken S
,
Gautier P
,
Reinholt FR,
Hirst RA
,
O'Callaghan C,
Heimdal K
,
Bottier M
,
Escudier E
,
Crowley S
,
Descartes M
,
Jabs EW
,
Kenia P,
Amiel J
,
Bacci GM
,
Calogero C
,
Palazzo V
,
Tiberi L
,
Blumlein U,
Rogers A,
Wambach JA
,
Wegner DJ
,
Fulton AB
,
Kenna M
,
Rosenfeld M,
Holm IA,
Quigley A
,
Hall EA
,
Murphy LC
,
Cassidy DM
,
von Kriegsheim A
,
Papon JF,
Pasquier L
,
Murris MS
,
Chalmers JD
,
Hogg C
,
Macleod KA,
Urquhart DS,
Unger S,
Aitman TJ
,
Amselem S
,
Leigh MW
,
Knowles MR
,
Omran H
,
Mitchison HM
,
Brown A
,
Marsh JA,
Welburn JPI,
Ti SC
,
Horani A
,
Rozet JM
,
Perrault I,
Mill P
(2024) Science , 384 , eadf5489 - eadf5489
,
Mechaussier S
,
Yeyati PL
,
McPhie F
,
Anderson JR
,
Khoo CJ
,
Shoemark A
,
Gupta DK
,
Attard T,
Zariwala MA
,
Legendre M
,
Bracht D
,
Wallmeier J
,
Gui M,
Fassad MR
,
Parry DA
,
Tennant PA
,
Meynert A
,
Wheway G
,
Fares-Taie L
,
Black HA
,
Mitri-Frangieh R,
Faucon C,
Kaplan J,
Patel M
,
McKie L
,
Megaw R
,
Gatsogiannis C,
Mohamed MA,
Aitken S
,
Gautier P
,
Reinholt FR,
Hirst RA
,
O'Callaghan C,
Heimdal K
,
Bottier M
,
Escudier E
,
Crowley S
,
Descartes M
,
Jabs EW
,
Kenia P,
Amiel J
,
Bacci GM
,
Calogero C
,
Palazzo V
,
Tiberi L
,
Blumlein U,
Rogers A,
Wambach JA
,
Wegner DJ
,
Fulton AB
,
Kenna M
,
Rosenfeld M,
Holm IA,
Quigley A
,
Hall EA
,
Murphy LC
,
Cassidy DM
,
von Kriegsheim A
,
Papon JF,
Pasquier L
,
Murris MS
,
Chalmers JD
,
Hogg C
,
Macleod KA,
Urquhart DS,
Unger S,
Aitman TJ
,
Amselem S
,
Leigh MW
,
Knowles MR
,
Omran H
,
Mitchison HM
,
Brown A
,
Marsh JA,
Welburn JPI,
Ti SC
,
Horani A
,
Rozet JM
,
Perrault I,
Mill P
(2024) Science , 384 , eadf5489 - eadf5489
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): 5R01GM141109 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): 5F30HL162128 (United States)
- The Pew Charitable Trusts: (United States)
