Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-40468
In situ human cardiac thick filament in the relaxed state
EMD-40468
Subtomogram averaging16.5 Å
Deposition: 13/04/2023Map released: 21/02/2024
Last modified: 05/06/2024
Sample Organism:
Homo sapiens
Sample: In situ human cardiac thick filament in the relaxed state
Deposition Authors: Chen L
,
Liu J
,
Rastegarpouyani H
,
Janssen PML
,
Pinto JR
,
Taylor KA
Sample: In situ human cardiac thick filament in the relaxed state
Deposition Authors: Chen L
,
Liu J
,
Rastegarpouyani H
,
Janssen PML
,
Pinto JR
,
Taylor KA
Structure of mavacamten-free human cardiac thick filaments within the sarcomere by cryoelectron tomography.
Chen L
,
Liu J
,
Rastegarpouyani H
,
Janssen PML
,
Pinto JR
,
Taylor KA
(2024) PNAS , 121 , e2311883121 - e2311883121
,
Liu J
,
Rastegarpouyani H
,
Janssen PML
,
Pinto JR
,
Taylor KA
(2024) PNAS , 121 , e2311883121 - e2311883121
Grant Support:
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): HL128683 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): HL160966 (United States)
- National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH/NIAMS): R21 AR077802 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R01AI087846 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R01AI152421 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35 GM139616 (United States)
