EMD-40462

Single-particle
2.65 Å
EMD-40462
3D View Gallery
Deposition: 12/04/2023
Map released: 30/08/2023
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40462
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8sgo summary report (pdf.gz) Map and 8sgo FULL report (pdf.gz)
EMICSS annotations (xml)

Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus pregnenolone sulfate

EMD-40462

Single-particle
2.65 Å
EMD-40462
3D View Gallery
Deposition: 12/04/2023
Map released: 30/08/2023
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Human GABA-A receptor alpha1-beta2-gamma2 subtype in complex with GABA and pregnenolone sulfate
Fitted models: 8sgo

Deposition Authors: Legesse DH, Fan C , Teng J, Zhuang Y , Howard RJ , Noviello CM, Lindahl E , Hibbs RE
Structural insights into opposing actions of neurosteroids on GABA A receptors.
Legesse DH, Fan C , Teng J, Zhuang Y , Howard RJ , Noviello CM, Lindahl E , Hibbs RE
(2023) Nat Commun , 14 , 5091 - 5091
PUBMED: 37607940
DOI: doi:10.1038/s41467-023-40800-1
ISSN: 2041-1723