EMD-40462
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus pregnenolone sulfate
EMD-40462
Single-particle2.65 Å
Deposition: 12/04/2023Map released: 30/08/2023
Last modified: 20/11/2024
Sample Organism:
Homo sapiens,
Mus musculus
Sample: Human GABA-A receptor alpha1-beta2-gamma2 subtype in complex with GABA and pregnenolone sulfate
Fitted models: 8sgo
Deposition Authors: Legesse DH, Fan C
,
Teng J,
Zhuang Y ,
Howard RJ ,
Noviello CM,
Lindahl E ,
Hibbs RE
Sample: Human GABA-A receptor alpha1-beta2-gamma2 subtype in complex with GABA and pregnenolone sulfate
Fitted models: 8sgo
Deposition Authors: Legesse DH, Fan C
,
Teng J,
Zhuang Y ,
Howard RJ ,
Noviello CM,
Lindahl E ,
Hibbs RE
Structural insights into opposing actions of neurosteroids on GABA A receptors.
Legesse DH,
Fan C ,
Teng J,
Zhuang Y ,
Howard RJ ,
Noviello CM,
Lindahl E ,
Hibbs RE
(2023) Nat Commun , 14 , 5091 - 5091
,
Teng J,
Zhuang Y ,
Howard RJ ,
Noviello CM,
Lindahl E ,
Hibbs RE
(2023) Nat Commun , 14 , 5091 - 5091
Grant Support:
- National Institutes of Health/National Institute on Drug Abuse (NIH/NIDA): DA047325 (United States)
- National Institutes of Health/National Institute on Drug Abuse (NIH/NIDA): DA051176 (United States)
- Welch Foundation: I-1812 (United States)