EMD-40337

Single-particle
3.46 Å
EMD-40337
3D View Gallery
Deposition: 04/04/2023
Map released: 18/10/2023
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40337

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8sc4 summary report (pdf.gz) Map-8sc4 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human OCT1 bound to metformin in inward-open conformation

EMD-40337

Single-particle
3.46 Å
EMD-40337
3D View Gallery
Deposition: 04/04/2023
Map released: 18/10/2023
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human OCT1
Fitted models: 8sc4

Deposition Authors: Zeng YC , Sobti M, Stewart AG
Structural basis of promiscuous substrate transport by Organic Cation Transporter 1.
Zeng YC , Sobti M, Quinn A , Smith NJ , Brown SHJ , Vandenberg JI , Ryan RM , O'Mara ML , Stewart AG
(2023) Nat Commun , 14 , 6374 - 6374
PUBMED: 37821493
DOI: doi:10.1038/s41467-023-42086-9
ISSN: 2041-1723