EMD-39771

Single-particle
3.4 Å
EMD-39771
3D View Gallery
Deposition: 17/04/2024
Map released: 05/02/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39771
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8z4x summary report (pdf.gz) Map and 8z4x FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of SARS-CoV-2 D614G S with two ACE2 receptors binding (RB2) in prefusion conformation

EMD-39771

Single-particle
3.4 Å
EMD-39771
3D View Gallery
Deposition: 17/04/2024
Map released: 05/02/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: D614G spike protein (S) in complex with two ACE2s
Fitted models: 8z4x

Deposition Authors: Liu Z, Xing L
Early fusion intermediate of ACE2-using coronavirus spike acting as an antiviral target.
Xing L, Liu Z, Wang X, Liu Q, Xu W, Mao Q, Zhang X, Hao A, Xia S, Liu Z, Sun L, Zhang G, Wang Q, Chen Z, Jiang S, Sun L, Lu L
(2025) Cell , 188 , 1297 - 1314.e24
PUBMED: 39889696
DOI: doi:10.1016/j.cell.2025.01.012
ISSN: 1097-4172