EMD-39594

Single-particle
3.0 Å
EMD-39594
3D View Gallery
Deposition: 28/03/2024
Map released: 31/07/2024
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39594

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8yv8 summary report (pdf.gz) Map-8yv8 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of CDCA7 bound to nucleosome including hemimethylated CpG site in Widom601 positioning sequence.

EMD-39594

Single-particle
3.0 Å
EMD-39594
3D View Gallery
Deposition: 28/03/2024
Map released: 31/07/2024
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: CDCA7 bound to nucleosome
Fitted models: 8yv8

Deposition Authors: Kikuchi A , Shikimachi R, Nishiyama A , Funabiki H , Arita K
CDCA7 is an evolutionarily conserved hemimethylated DNA sensor in eukaryotes.
Wassing IE , Nishiyama A , Shikimachi R, Jia Q , Kikuchi A , Hiruta M, Sugimura K, Hong X, Chiba Y, Peng J, Jenness C, Nakanishi M, Zhao L , Arita K , Funabiki H
(2024) Sci Adv , 10 , eadp5753 - eadp5753
PUBMED: 39178260
DOI: doi:10.1126/sciadv.adp5753
ISSN: 2375-2548