EMD-39010

Single-particle
2.65 Å
EMD-39010
3D View Gallery
Deposition: 03/02/2024
Map released: 06/08/2025
Last modified: 11/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39010
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8y72 summary report (pdf.gz) Map and 8y72 FULL report (pdf.gz)
EMICSS annotations (xml)

positive allosteric modulator(BMS986122)-bound mu-opioid receptor-Gi complex

EMD-39010

Single-particle
2.65 Å
EMD-39010
3D View Gallery
Deposition: 03/02/2024
Map released: 06/08/2025
Last modified: 11/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Rattus norvegicus, Bos taurus
Sample: positive allosteric modulator(BMS986122)-bound mu-opioid receptor-Gi complex
Fitted models: 8y72

Deposition Authors: Luo P , Xu Y , Wang Y , Zhuang Y , Xu HE
Structure-based design of an opioid receptor modulator for enhanced morphine analgesia.
Wang Y , Luo P , Xu H, Zhan L, Sakamoto K , Li M, Wang J , Huang XP , Zhou J , Liu T, Suo Y , Fan W, He X , Xu Y , Cai Y, Wang C , Zhao Y, Dai A , Lai Y, Yuan Q, Hu W , Wu K, Yang D , Cheng X , Lu X , Krumm B, Kenakin T , Zhang J , Roth BL , Gao Z , Xu HE , Zhuang Y
(2026) Sci Adv , 12 , eaea9832 - eaea9832
PUBMED: 41671375
DOI: doi:10.1126/sciadv.aea9832
ISSN: 2375-2548