EMD-38847

Single-particle
4.2 Å
EMD-38847
3D View Gallery
Deposition: 25/01/2024
Map released: 22/01/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-38847
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8y1v summary report (pdf.gz) Map and 8y1v FULL report (pdf.gz)
EMICSS annotations (xml)

GluN1b-GluN2D NMDA receptor in complex with competitive antagonist R-CPP and allosteric inhibitor YY-23

EMD-38847

Single-particle
4.2 Å
EMD-38847
3D View Gallery
Deposition: 25/01/2024
Map released: 22/01/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: N-methyl-D-aspartate receptors
Fitted models: 8y1v

Deposition Authors: Zhang JL , Zhu SJ, Guo F
An antidepressant mechanism underlying the allosteric inhibition of GluN2D-incorporated NMDA receptors at GABAergic interneurons.
Zhang J, Duan J, Li W, Wang X, Ren S, Ye L, Liu F, Tian X, Xie Y, Huang Y, Sun Y, Song N, Li T, Cai X, Liu Z, Zhou H, Huang C, Li Y, Zhu S , Guo F
(2025) Sci Adv , 11 , eadq0444 - eadq0444
PUBMED: 40043126
DOI: doi:10.1126/sciadv.adq0444
ISSN: 2375-2548