EMD-38154
Fab domain of Immunoglobulin (IgG) reconstruction using phase plate single-particle cryo-EM
EMD-38154
Single-particle6.64 Å
Deposition: 28/11/2023Map released: 27/11/2024
Last modified: 04/12/2024
Sample Organism:
Mus musculus
Sample: Fab domain of Rituximab
Deposition Authors: Lin HH
,
Wang CH ,
Wu YM ,
Tu IP ,
Chang WH
Sample: Fab domain of Rituximab
Deposition Authors: Lin HH
,
Wang CH ,
Wu YM ,
Tu IP ,
Chang WH
Use of phase plate cryo-EM reveals conformation diversity of therapeutic IgG with 50 kDa Fab fragment resolved below 6 angstrom.
Lin HH ,
Wang CH ,
Huang SH,
Lin SY ,
Kato T,
Namba K ,
Hosogi N,
Song C ,
Murata K ,
Yen CH,
Hsu TL ,
Wong CH,
Wu YM ,
Tu IP ,
Chang WH
(2024) Sci Rep , 14 , 14079 - 14079
,
Wang CH ,
Huang SH,
Lin SY ,
Kato T,
Namba K ,
Hosogi N,
Song C ,
Murata K ,
Yen CH,
Hsu TL ,
Wong CH,
Wu YM ,
Tu IP ,
Chang WH
(2024) Sci Rep , 14 , 14079 - 14079
Grant Support:
- Academia Sinica (Taiwan): AS-SUMMIT-107 (Taiwan)
- Academia Sinica (Taiwan): AS-SUMMIT-108 (Taiwan)
- Academia Sinica (Taiwan): AS-SUMMIT-109 (Taiwan)
- Academia Sinica (Taiwan): AS-GCS-108-08 (Taiwan)
- Academia Sinica (Taiwan): AS-IA-110-M05 (Taiwan)
- Academia Sinica (Taiwan): AS-GCS-112-M03 (Taiwan)