EMDB EMD-3805

Single particle reconstruction
3.8Å resolution

Cryo-EM structure of jasplakinolide-stabilized malaria parasite F-actin at near-atomic resolution

Map released:
Last modified:
Overview of EMD-3805
Source organism: Plasmodium falciparum (isolate HB3) [137071]
Fitted atomic model: 5ogw
Primary publication:
Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability.
Pospich S, Kumpula EP, von der Ecken J, Vahokoski J, Kursula I, Raunser S
Proc. Natl. Acad. Sci. U.S.A. 114 10636-10641 (2017)
PMID: 28923924

Function and Biology Details

Sample name: Plasmodium falciparum actin 1 filament stabilized by jasplakinolide
Ligands: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Jasplakinolide
Proteins: Plasmodium falciparum actin 1 filament stabilized by jasplakinolide, Actin-1

Experimental Information Details

Resolution: 3.8Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON II (4k x 4k)