EMD-37210

Single-particle
3.17 Å
EMD-37210
3D View Gallery
Deposition: 17/08/2023
Map released: 19/06/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-37210

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8kg5 summary report (pdf.gz) Map-8kg5 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Prefusion RSV F Bound to Lonafarnib and D25 Fab

EMD-37210

Single-particle
3.17 Å
EMD-37210
3D View Gallery
Deposition: 17/08/2023
Map released: 19/06/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human respiratory syncytial virus A (strain A2), Enterobacteria phage T4
Sample: Prefusion RSV F Bound to Lonafarnib and D25 Fab
Fitted models: 8kg5

Deposition Authors: Yang Q, Xue B, Liu F , Peng W, Chen X
Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein.
Yang Q, Xue B, Liu F , Lu Y, Tang J, Yan M, Wu Q, Chen R, Zhou A, Liu L, Liu J, Qu C, Wu Q, Fu M, Zhong J, Dong J, Chen S, Wang F , Zhou Y, Zheng J, Peng W, Shang J , Chen X
(2024) Signal Transduct Target Ther , 9 , 144 - 144
PUBMED: 38853183
DOI: doi:10.1038/s41392-024-01858-5
ISSN: 2059-3635