EMD-36736

Single-particle
2.6 Å
EMD-36736
3D View Gallery
Deposition: 04/07/2023
Map released: 04/10/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-36736

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8jz7 summary report (pdf.gz) Map-8jz7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of MK-6892-bound HCAR2 in complex with Gi protein

EMD-36736

Single-particle
2.6 Å
EMD-36736
3D View Gallery
Deposition: 04/07/2023
Map released: 04/10/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: HCA2 in complex with Gi heterotrimer
Fitted models: 8jz7

Deposition Authors: Zhao C , Tian XW, Liu Y, Cheng L, Yan W, Shao ZH
Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2.
Cheng L, Sun S, Wang H, Zhao C , Tian X, Liu Y, Fu P , Shao Z , Chai R , Yan W
(2023) Signal Transduct Target Ther , 8 , 364 - 364
PUBMED: 37743365
DOI: doi:10.1038/s41392-023-01625-y
ISSN: 2059-3635