EMD-35601
Cryo-EM structure of the alpha-MSH-bound human melanocortin receptor 5 (MC5R)-Gs complex
EMD-35601
Single-particle2.73 Å
Deposition: 10/03/2023Map released: 20/09/2023
Last modified: 23/10/2024
Sample Organism:
Homo sapiens,
synthetic construct,
Bos taurus
Sample: Cryo-EM structure of alpha-MSH-bound human melanocortin receptor 5 in complex with G protein
Fitted models: 8inr
Deposition Authors: Feng WB, Zhou QT, Chen XY, Dai AT, Cai XQ, Liu X, Zhao FH, Chen Y, Ye CY, Xu YN, Cong ZT, Li H, Lin S, Yang DH, Wang MW
Sample: Cryo-EM structure of alpha-MSH-bound human melanocortin receptor 5 in complex with G protein
Fitted models: 8inr
Deposition Authors: Feng WB, Zhou QT, Chen XY, Dai AT, Cai XQ, Liu X, Zhao FH, Chen Y, Ye CY, Xu YN, Cong ZT, Li H, Lin S, Yang DH, Wang MW
Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors.
Feng W,
Zhou Q
,
Chen X,
Dai A,
Cai X,
Liu X,
Zhao F,
Chen Y,
Ye C,
Xu Y,
Cong Z,
Li H,
Lin S,
Yang D
,
Wang MW
(2023) Cell Discov , 9 , 81
,
Chen X,
Dai A,
Cai X,
Liu X,
Zhao F,
Chen Y,
Ye C,
Xu Y,
Cong Z,
Li H,
Lin S,
Yang D
,
Wang MW
(2023) Cell Discov , 9 , 81
Grant Support:
- National Natural Science Foundation of China (NSFC): 81872915 (China)
- National Natural Science Foundation of China (NSFC): 82073904 (China)
- National Natural Science Foundation of China (NSFC): 82121005 (China)
- National Natural Science Foundation of China (NSFC): 81973373 (China)
- National Natural Science Foundation of China (NSFC): 21704064 (China)
- Other government: 2018YFA0507000
- Other government: 2018ZX09735-001
- Other government: 2018ZX09711002-002-005
- Other government: STI2030-Major project 2021ZD0203400
- Other government: ZDKJ2021028
- Other government: 21JC1401600
