EMD-35535

Single-particle
4.3 Å
EMD-35535 Deposition: 03/03/2023
Map released: 16/08/2023
Last modified: 16/08/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-35535

Human ornithine transcarbamylase expressed using mRNA lipid nanoparticles in human cells and PEGylated

EMD-35535

Single-particle
4.3 Å
EMD-35535 Deposition: 03/03/2023
Map released: 16/08/2023
Last modified: 16/08/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human ornithine transcarbamylase

Deposition Authors: Kondo K , Yamazaki K , Kubara K , Ishii S , Suzuki Y, Miyazaki T, Mitsuhashi K, Ito M, Tsukahara K
Lipid nanoparticle-targeted mRNA formulation as a treatment for ornithine-transcarbamylase deficiency model mice.
Yamazaki K , Kubara K , Ishii S , Kondo K , Suzuki Y, Miyazaki T, Mitsuhashi K, Ito M, Tsukahara K
(2023) Mol Ther Nucleic Acids , 33 , 210 - 226
PUBMED: 37520683
DOI: doi:10.1016/j.omtn.2023.06.023
ISSN: 2162-2531
Grant Support: