EMD-35526

Single-particle
3.86 Å
EMD-35526
3D View Gallery
Deposition: 01/03/2023
Map released: 29/03/2023
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-35526
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8il3 summary report (pdf.gz) Map and 8il3 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of CD38 in complex with FTL004

EMD-35526

Single-particle
3.86 Å
EMD-35526
3D View Gallery
Deposition: 01/03/2023
Map released: 29/03/2023
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of CD38 in complex with FTL004
Fitted models: 8il3

Deposition Authors: Yang J, Wang Y, Zhang G
FTL004, an anti-CD38 mAb with negligible RBC binding and enhanced pro-apoptotic activity, is a novel candidate for treatments of multiple myeloma and non-Hodgkin lymphoma.
Zhang G, Guo C, Wang Y, Zhang X, Liu S, Qu W, Chen C, Yan L, Yang Z, Zhang Z, Jiang X, Chen X, Liu H, Lai Q, Wei X, Lu Y, Zhao S, Deng H, Wang Y, Yu L, Yu H, Wu Y, Su Z, Chen P, Ren Z, Yu M, Qu F, Luo Y, Gou L, Li Q, Huang Y, Ma F, Yang J
(2022) J Hematol Oncol , 15 , 177 - 177
PUBMED: 36581954
DOI: doi:10.1186/s13045-022-01395-0
ISSN: 1756-8722