EMD-33443

Single-particle
3.2 Å
EMD-33443
3D View Gallery
Deposition: 16/05/2022
Map released: 27/07/2022
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-33443
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7xt9 summary report (pdf.gz) Map and 7xt9 FULL report (pdf.gz)
EMICSS annotations (xml)

Serotonin 4 (5-HT4) receptor-Gs complex

EMD-33443

Single-particle
3.2 Å
EMD-33443
3D View Gallery
Deposition: 16/05/2022
Map released: 27/07/2022
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Serotonin 4 (5-HT4) receptor-Gs complex
Fitted models: 7xt9

Deposition Authors: Huang S, Xu P, Shen DD, Simon IA , Mao C, Tan Y, Zhang H, Harpsoe K , Li H, Zhang Y, You C, Yu X, Jiang Y, Zhang Y, Gloriam DE , Xu HE
GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors.
Huang S, Xu P, Shen DD, Simon IA , Mao C, Tan Y, Zhang H, Harpsoe K , Li H, Zhang Y, You C, Yu X, Jiang Y, Zhang Y, Gloriam DE , Xu HE
(2022) Mol Cell , 82 , 2681 - 2695.e6
PUBMED: 35714614
DOI: doi:10.1016/j.molcel.2022.05.031
ISSN: 1097-2765
ASTM: MOCEFL