EMDB EMD-3338

Single particle reconstruction
4.0Å resolution

Atomic cryoEM structure of Hsp90/Cdc37/Cdk4 complex

Map released:
Last modified:
Overview of EMD-3338
Source organism: Homo sapiens [9606]
Related EM entries by publication: EMD-3337, EMD-3339, EMD-3340, EMD-3341, EMD-3342, EMD-3343, EMD-3344
Primary publication:
Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase
Verba KA, Wang RYR, Arakawa A, Liu Y, Shirouzu M, Yokoyama S, Agard DA
SCIENCE 352 1542-1547 (2016)
PMID: 27339980

Function and Biology Details

Sample name: Complex of Human Hsp90 beta, human Cdc37 and human Cdk4
Proteins: Heat Shock Protein HSP 90 beta, Hsp90 co-chaperone Cdc37, Cyclin-dependent kinase 4

Experimental Information Details

Resolution: 4.0Å
Resolution method: FSC 0.143, gold-standard
Applied symmetry: C1
Reconstruction software: Relion
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)