EMD-33126

Single-particle
2.57 Å
EMD-33126
3D View Gallery
Deposition: 25/03/2022
Map released: 20/04/2022
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-33126

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7xcr summary report (pdf.gz) Map-7xcr FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 1:1 complex

EMD-33126

Single-particle
2.57 Å
EMD-33126
3D View Gallery
Deposition: 25/03/2022
Map released: 20/04/2022
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Complex of Dot1L(1-416) and H2BK34ub nucleosome
Fitted models: 7xcr

Deposition Authors: Ai HS, Liu AJ, Lou ZY, Liu L
H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Ai H , Sun M , Liu A, Sun Z, Liu T, Cao L, Liang L, Qu Q, Li Z, Deng Z, Tong Z, Chu G, Tian X, Deng H , Zhao S , Li JB , Lou Z , Liu L
(2022) Nat Chem Biol , 18 , 972 - 980
PUBMED: 35739357
DOI: doi:10.1038/s41589-022-01067-7
ISSN: 1552-4469