EMD-32599

Single-particle
3.2 Å
EMD-32599
3D View Gallery
Deposition: 14/01/2022
Map released: 25/01/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-32599

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7wm4 summary report (pdf.gz) Map-7wm4 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of tetrameric TLR3 in complex with dsRNA (90 bp)

EMD-32599

Single-particle
3.2 Å
EMD-32599
3D View Gallery
Deposition: 14/01/2022
Map released: 25/01/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, synthetic construct
Sample: Tetrameric TLR3 in complex with dsRNA (90 bp)
Fitted models: 7wm4

Deposition Authors: Sakaniwa K, Ohto U
TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction.
Sakaniwa K, Fujimura A, Shibata T , Shigematsu H , Ekimoto T, Yamamoto M, Ikeguchi M, Miyake K , Ohto U , Shimizu T
(2023) Nat Commun , 14 , 164 - 164
PUBMED: 36631495
DOI: doi:10.1038/s41467-023-35844-2
ISSN: 2041-1723