EMD-32495

Single-particle
3.7 Å
EMD-32495
3D View Gallery
Deposition: 29/12/2021
Map released: 02/02/2022
Last modified: 24/08/2022
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-32495

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

C1 map of TM domain of human Kv1.3 channel in dalazatide-bound state

EMD-32495

Single-particle
3.7 Å
EMD-32495
3D View Gallery
Deposition: 29/12/2021
Map released: 02/02/2022
Last modified: 24/08/2022
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: C1 map of TM domain of human Kv1.3 channel in dalazatide-bound state

Deposition Authors: Tyagi A , Ahmed T, Jian S, Bajaj S , Ong ST , Goay SSM , Zhao Y, Vorobyov I , Tian C, Chandy KG , Bhushan S
Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug.
Tyagi A , Ahmed T, Jian S, Bajaj S , Ong ST , Goay SSM , Zhao Y, Vorobyov I , Tian C, Chandy KG , Bhushan S
(2022) PNAS , 119
PUBMED: 35091471
DOI: doi:10.1073/pnas.2113536119
ISSN: 1091-6490
ASTM: PNASA6