EMD-3238

Single-particle
4.1 Å
EMD-3238
3D View Gallery
Deposition: 10/11/2015
Map released: 09/12/2015
Last modified: 16/12/2015
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-3238

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-5fn3 summary report (pdf.gz) Map-5fn3 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of gamma secretase in class 1 of the apo-state ensemble

EMD-3238

Single-particle
4.1 Å
EMD-3238
3D View Gallery
Deposition: 10/11/2015
Map released: 09/12/2015
Last modified: 16/12/2015
Overview 3D View Sample Experiment Validation Additional data Links
Name: human gamma secretase in class 1 of the apo-state ensemble
Sample [1]
Name: human gamma secretase in class 1 of the apo-state ensemble
Number of unique components: 1
Oligomeric state: Heterotetramer
Molecular weight
Experimental Theoretical Method
170 kDa 170 kDa -
Protein [1]
Recombinant expression
Name: gamma-secretase
Number of copies: 1
Oligomeric state: Heterotetramer
UniProtKB PDBe-KB AlphaFold DB
Natural source
Organism: Homo sapiens (Human)
Cell: HEK293F
Cellular location: membrane
Molecular weight
Experimental Theoretical Method
170 kDa 170 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - HEK 293F pMLink