EMD-32370

Single-particle
3.0 Å
EMD-32370
3D View Gallery
Deposition: 10/12/2021
Map released: 25/05/2022
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-32370

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7w9m summary report (pdf.gz) Map-7w9m FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of human Nav1.7(E406K) in complex with auxiliary beta subunits, ProTx-II and tetrodotoxin (S6IV pi helix conformer)

EMD-32370

Single-particle
3.0 Å
EMD-32370
3D View Gallery
Deposition: 10/12/2021
Map released: 25/05/2022
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human voltage-gated sodium channel Nav1.7 in complex with auxiliary beta subunits
Fitted models: 7w9m

Deposition Authors: Yan N, Huang G, Liu D, Wei P, Shen H
High-resolution structures of human Na v 1.7 reveal gating modulation through alpha-pi helical transition of S6 IV.
Huang G, Liu D, Wang W, Wu Q, Chen J, Pan X , Shen H, Yan N
(2022) Cell Rep , 39 , 110735 - 110735
PUBMED: 35476982
DOI: doi:10.1016/j.celrep.2022.110735
ISSN: 2211-1247