EMDB EMD-31149

Single particle reconstruction
3.3Å resolution

human voltage-gated potassium channel KV1.3 H451N mutant

Map released:
Overview of EMD-31149
Source organism: Homo sapiens [9606]
Fitted atomic model: 7ej2
Primary publication:
Structures of wild-type and H451N mutant human lymphocyte potassium channel K V 1.3.
Liu S, Zhao Y, Dong H, Xiao L, Zhang Y, Yang Y, Ong ST, Chandy KG, Zhang L, Tian C
Cell Discov 7 39-39 (2021)
PMID: 34059645

Function and Biology Details

Sample name: Human KV1.3 H451N-KVb2.1
Ligand: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Proteins: Human KV1.3 H451N-KVb2.1, Voltage-gated potassium channel subunit beta-2, Potassium voltage-gated channel subfamily A member 3

Experimental Information Details

Resolution: 3.3Å
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)