EMD-30700

Single-particle
2.8 Å
EMD-30700
3D View Gallery
Deposition: 21/11/2020
Map released: 19/05/2021
Last modified: 15/11/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-30700

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7djt summary report (pdf.gz) Map-7djt FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Human SARM1 inhibitory state bounded with inhibitor dHNN

EMD-30700

Single-particle
2.8 Å
EMD-30700
3D View Gallery
Deposition: 21/11/2020
Map released: 19/05/2021
Last modified: 15/11/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human NAD(+) hydrolysis SARM1
Fitted models: 7djt

Deposition Authors: Cai Y , Zhang H
Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate.
Li WH , Huang K, Cai Y , Wang QW, Zhu WJ , Hou YN, Wang S, Cao S, Zhao ZY, Xie XJ, Du Y, Lee CS, Lee HC , Zhang H , Zhao YJ
(2021) eLife , 10
PUBMED: 33944777
DOI: doi:10.7554/eLife.67381
ISSN: 2050-084X