EMDB EMD-3061

Single particle reconstruction
3.4Å resolution

Cryo-EM structure of the human gamma-secretase complex at 3.4 angstrom resolution.

Map released:
Last modified:
Overview of EMD-3061
Source organism: Homo sapiens [9606]
Fitted atomic model: 5a63
Primary publication:
An atomic structure of human gamma-secretase
Bai XC, Yan CY, Yang GH, Lu PL, Ma D, Sun LF, Zhou R, Scheres SHW, Shi YG
NATURE 525 212-217 (2015)
PMID: 26280335

Function and Biology Details

Sample name: human gamma-secretase
Protein: gamma-secretase

Experimental Information Details

Resolution: 3.4Å
Resolution method: FSC 0.143, gold-standard
Applied symmetry: C1
Reconstruction software: CTFFIND3, RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 (4k x 4k)