EMDB EMD-30578

Single particle reconstruction
3.1Å resolution

cryo-EM structure of human RNA polymerase III in apo state

Map released:
Last modified:
Overview of EMD-30578
Source organism: Human [9606]
Fitted atomic model: 7d59
Primary publication:
Structural insights into transcriptional regulation of human RNA polymerase III.
Wang Q, Li S, Wan F, Xu Y, Wu Z, Cao M, Lan P, Lei M, Wu J
Nat.Struct.Mol.Biol. 28 220-227 (2021)
PMID: 33558766

Function and Biology Details

Sample name: RNA Pol3 Apo
Ligands: ZINC ION, IRON/SULFUR CLUSTER
Proteins: RNA Pol3 Apo, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC2, DNA-directed RNA polymerases I and III subunit RPAC1, DNA-directed RNA polymerase III subunit RPC9, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase III subunit RPC8, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerases I and III subunit RPAC2, DNA-directed RNA polymerases I, II, and III subunit RPABC4, DNA-directed RNA polymerase III subunit RPC5, DNA-directed RNA polymerase III subunit RPC4, DNA-directed RNA polymerase III subunit RPC3, DNA-directed RNA polymerase III subunit RPC6, DNA-directed RNA polymerase III subunit RPC7

Experimental Information Details

Resolution: 3.1Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: OTHER