EMDB EMD-30460

Single particle reconstruction
4.0Å resolution

cryo EM map of the S protein of SARS-CoV-2 in complex bound with T-ACE2

Map released:
Last modified:
Overview of EMD-30460
Fitted atomic model: 7ct5
Primary publication:
Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection.
Guo L, Bi W, Wang X, Xu W, Yan R, Zhang Y, Zhao K, Li Y, Zhang M, Cai X, Jiang S, Xie Y, Zhou Q, Lu L, Dang B
Cell Res. - (2020)
PMID: 33177651

Function and Biology Details

Sample name: S protein of SARS-CoV-2 in complex bound with ACE2
Ligand: 2-acetamido-2-deoxy-beta-D-glucopyranose
Proteins: S protein of SARS-CoV-2 in complex bound with ACE2, S protein of SARS-CoV-2, ACE2, Spike glycoprotein, Angiotensin-converting enzyme 2

Experimental Information Details

Resolution: 4.0Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: OTHER