EMDB EMD-30267

Single particle reconstruction
3.9Å resolution

Human cGAS-nucleosome complex

Map released:
Last modified:
Overview of EMD-30267
Source organisms:
Fitted atomic model: 7c0m
Primary publication:
Structural basis for the inhibition of cGAS by nucleosomes.
Kujirai T, Zierhut C, Takizawa Y, Kim R, Negishi L, Uruma N, Hirai S, Funabiki H, Kurumizaka H
Science - (2020)
PMID: 32912999

Function and Biology Details

Sample name: Human cGAS-nucleosome complex
Ligand: ZINC ION
Nucleic acids: DNA (145-MER), DNA (145-MER)
Proteins: Human cGAS-nucleosome complex, Histone H3.1, Histone H4, Histone H2A type 1-B/E, Histone H2B type 1-J, Cyclic GMP-AMP synthase

Experimental Information Details

Resolution: 3.9Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: TFS KRIOS
Detector: OTHER