EMD-29743

Single-particle
2.89 Å
EMD-29743
3D View Gallery
Deposition: 13/02/2023
Map released: 20/09/2023
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29743

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8g5h summary report (pdf.gz) Map-8g5h FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Native GABA-A receptor from the mouse brain, ortho-alpha1-alpha3-beta2-gamma2 subtype, in complex with GABA, Zolpidem, and endogenous neurosteroid

EMD-29743

Single-particle
2.89 Å
EMD-29743
3D View Gallery
Deposition: 13/02/2023
Map released: 20/09/2023
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Native GABAA Receptor isolated from mouse brain containing one alpha1 subunit, in complex with 8E3-Fab, GABA, Zolpidem, and endogenous neurosteroid
Fitted models: 8g5h

Deposition Authors: Sun C, Gouaux E
Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology.
Sun C, Zhu H, Clark S, Gouaux E
(2023) Nature , 622 , 195 - 201
PUBMED: 37730991
DOI: doi:10.1038/s41586-023-06556-w
ISSN: 1476-4687
ASTM: NATUAS