EMD-29644

Single-particle
3.4 Å
EMD-29644
3D View Gallery
Deposition: 31/01/2023
Map released: 30/08/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29644
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8g04 summary report (pdf.gz) Map and 8g04 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of signaling thrombopoietin-MPL receptor complex

EMD-29644

Single-particle
3.4 Å
EMD-29644
3D View Gallery
Deposition: 31/01/2023
Map released: 30/08/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Thrombopoietin signaling complex with two thrombopoietin receptor chains
Fitted models: 8g04

Deposition Authors: Tsutsumi N , Jude KM, Gati C, Garcia KC
Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis.
Tsutsumi N , Masoumi Z , James SC, Tucker JA, Winkelmann H , Grey W , Picton LK, Moss L , Wilson SC , Caveney NA, Jude KM, Gati C, Piehler J, Hitchcock IS, Garcia KC
(2023) Cell , 186 , 4189 - 4203.e22
PUBMED: 37633268
DOI: doi:10.1016/j.cell.2023.07.037
ISSN: 1097-4172