Single particle reconstruction
3.6Å resolution

Cryo-EM structure of the human APC/C-Cdh1-Emi1 ternary complex at 3.6 angstrom resolution.

Map released:
Last modified:
Overview of EMD-2924
Source organism: Homo sapiens [9606]
Fitted atomic model: 4ui9
Related EM entry by publication: EMD-2925, EMD-2926
Primary publication:
Atomic structure of the APC/C and its mechanism of protein ubiquitination
Chang L, Zhang Z, Yang J, McLaughlin SH, Barford D
NATURE 522 450-454 (2015)
PMID: 26083744

Function and Biology Details

Sample name: Recombinant human APC/C-Cdh1-Emi1 ternary complex
Proteins: Apc1, Apc2, Apc3, Apc4, Apc5, Apc6, Apc7, Apc8, Apc10, Apc11, Apc12, Apc13, Apc15, Apc16, Cdh1, Emi1

Experimental Information Details

Resolution: 3.6Å
Resolution method: FSC 0.143, gold-standard
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI POLARA 300
Detector: FEI FALCON II (4k x 4k)