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EMD-29026
CryoEM structure of Kappa Opioid Receptor bound to a semi-peptide and Gi1
EMD-29026
Single-particle2.54 Å
Deposition: 06/12/2022Map released: 06/12/2023
Last modified: 04/06/2025
Sample Organism:
Homo sapiens,
Mus musculus,
synthetic construct
Sample: Kappa Opioid Receptor in complex with Gi1 heterotrimer and a peptide ligand
Fitted models: 8feg
Deposition Authors: Fay JF
,
Che T
Sample: Kappa Opioid Receptor in complex with Gi1 heterotrimer and a peptide ligand
Fitted models: 8feg
Deposition Authors: Fay JF
,
Che T
Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor.
Muratspahic E,
Deibler K ,
Han J,
Tomasevic N ,
Jadhav KB ,
Olive-Marti AL,
Hochrainer N,
Hellinger R,
Koehbach J,
Fay JF ,
Rahman MH,
Hegazy L,
Craven TW,
Varga BR,
Bhardwaj G,
Appourchaux K ,
Majumdar S ,
Muttenthaler M ,
Hosseinzadeh P ,
Craik DJ ,
Spetea M ,
Che T ,
Baker D ,
Gruber CW
(2023) Nat Commun , 14 , 8064
,
Han J,
Tomasevic N ,
Jadhav KB ,
Olive-Marti AL,
Hochrainer N,
Hellinger R,
Koehbach J,
Fay JF ,
Rahman MH,
Hegazy L,
Craven TW,
Varga BR,
Bhardwaj G,
Appourchaux K ,
Majumdar S ,
Muttenthaler M ,
Hosseinzadeh P ,
Craik DJ ,
Spetea M ,
Che T ,
Baker D ,
Gruber CW
(2023) Nat Commun , 14 , 8064
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