EMD-29012

Single-particle
3.2 Å
EMD-29012 Deposition: 04/12/2022
Map released: 21/06/2023
Last modified: 15/11/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29012

Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi

EMD-29012

Single-particle
3.2 Å
EMD-29012 Deposition: 04/12/2022
Map released: 21/06/2023
Last modified: 15/11/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Engineered human dynein motor domain in microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi
Fitted models: 8fdt

Deposition Authors: Ton W, Wang Y , Chai P
Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport.
Ton WD, Wang Y , Chai P , Beauchamp-Perez C, Flint NT, Lammers LG, Xiong H, Zhang K , Markus SM
(2023) Nat Struct Mol Biol , 30 , 1365 - 1379
PUBMED: 37322240
DOI: doi:10.1038/s41594-023-01010-x
ISSN: 1545-9985