EMD-28724

Single-particle
4.9 Å
EMD-28724
3D View Gallery
Deposition: 29/10/2022
Map released: 09/11/2022
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-28724
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8eyy summary report (pdf.gz) Map and 8eyy FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S, denoted as IR-3CS) Asymmetric conformation 2

EMD-28724

Single-particle
4.9 Å
EMD-28724
3D View Gallery
Deposition: 29/10/2022
Map released: 09/11/2022
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S; denoted as IR-3CS) Asymmetric conformation 2
Fitted models: 8eyy

Deposition Authors: Li J , Wu JY, Hall C, Bai XC, Choi E
Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Li J , Wu J , Hall C, Bai XC, Choi E
(2022) eLife , 11
PUBMED: 36413010
DOI: doi:10.7554/eLife.81286
ISSN: 2050-084X