EMD-28547
Cryo-EM structure of PRC2 in complex with the long isoform of AEBP2
EMD-28547
Single-particle3.64 Å
Deposition: 09/10/2022Map released: 31/07/2024
Last modified: 03/12/2025
Sample Organism:
Homo sapiens
Sample: Ternary complex of PRC2 with long isoform of AEBP2
Fitted models: 8eqv
Deposition Authors: Boudes M
,
Zhang Q ,
Flanigan SF,
Davidovich C
Sample: Ternary complex of PRC2 with long isoform of AEBP2
Fitted models: 8eqv
Deposition Authors: Boudes M
,
Zhang Q ,
Flanigan SF,
Davidovich C
Auto-inhibition of PRC2 by the broadly expressed long isoform of AEBP2.
Mucha M,
Lai Z,
McKenzie NJ,
Matra F,
Boudes M ,
Flanigan SF,
Alejo-Vinogradova MT,
Monger C,
Zhang Q ,
Nimmo D,
Healy E,
Silva AJ,
Angelov D,
Reck DM,
Holland G,
Atmaca ZE,
King HE,
Hamilton M,
Glancy E,
Nolan J,
Weatheritt RJ,
Bell O,
Vermeulen M,
Davidovich C ,
Bracken AP
(2025) EMBO J
,
Flanigan SF,
Alejo-Vinogradova MT,
Monger C,
Zhang Q ,
Nimmo D,
Healy E,
Silva AJ,
Angelov D,
Reck DM,
Holland G,
Atmaca ZE,
King HE,
Hamilton M,
Glancy E,
Nolan J,
Weatheritt RJ,
Bell O,
Vermeulen M,
Davidovich C ,
Bracken AP
(2025) EMBO J
Grant Support:
- Australian Research Council (ARC): DP190103407 (Australia)
- Other private: Sylvia and Charles Viertel Senior Medical Research Fellowship (Australia)
- National Health and Medical Research Council (NHMRC, Australia): APP1162921 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): APP1184637 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): APP2011767 (Australia)
- Australian Research Council (ARC): DE180100219 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): APP1196365 (Australia)