EMD-28228

Single-particle
3.6 Å
EMD-28228
3D View Gallery
Deposition: 24/09/2022
Map released: 19/07/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-28228
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8elj summary report (pdf.gz) Map and 8elj FULL report (pdf.gz)
EMICSS annotations (xml)

SARS-CoV-2 spike glycoprotein in complex with the ICO-hu23 neutralizing antibody Fab fragment

EMD-28228

Single-particle
3.6 Å
EMD-28228
3D View Gallery
Deposition: 24/09/2022
Map released: 19/07/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 spike glycoprotein in complex with the ICO-hu23 antibody Fab fragment
Fitted models: 8elj

Deposition Authors: Yee AW, Morizumi T, Kim K, Kuo A, Ernst OP
Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates.
Hermet P , Delache B, Herate C , Wolf E, Kivi G, Juronen E, Mumm K, Zusinaite E, Kainov D , Sankovski E, Virumae K, Planken A, Merits A , Besaw JE, Yee AW, Morizumi T, Kim K, Kuo A, Berriche A, Dereuddre-Bosquet N, Sconosciuti Q, Naninck T, Relouzat F, Cavarelli M, Ustav M, Wilson D, Ernst OP , Mannik A, LeGrand R, Ustav Jr M
(2023) PLoS Pathog , 19 , e1011532 - e1011532
PUBMED: 37531329
DOI: doi:10.1371/journal.ppat.1011532
ISSN: 1553-7374
Grant Support: