Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-28067

Single-particle
2.35 Å
EMD-28067
3D View Gallery
Deposition: 08/09/2022
Map released: 24/05/2023
Last modified: 06/12/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-28067
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

CryoEM reconstruction of tri-specific 298-52-80 Multabody (no symmetry applied)

EMD-28067

Single-particle
2.35 Å
EMD-28067
3D View Gallery
Deposition: 08/09/2022
Map released: 24/05/2023
Last modified: 06/12/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: tri-specific 298-52-80 Multabody

Deposition Authors: Kucharska I , Cui H, Rubinstein JL , Julien JP
A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo.
Burn Aschner C , Muthuraman K , Kucharska I , Cui H, Prieto K, Nair MS , Wang M, Huang Y , Christie-Holmes N , Poon B, Lam J , Sultana A, Kozak R, Mubareka S , Rubinstein JL , Rujas E , Treanor B , Ho DD, Jetha A , Julien JP
(2023) Sci Transl Med , 15 , eadf4549 - eadf4549
PUBMED: 37224226
DOI: doi:10.1126/scitranslmed.adf4549
ISSN: 1946-6242