EMD-27811

Single-particle
3.6 Å
EMD-27811
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Deposition: 08/08/2022
Map released: 30/08/2023
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27811
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Symmetry expansion of yeast cytoplasmic dynein-1 bound to Lis1 in the chi conformation.

EMD-27811

Single-particle
3.6 Å
EMD-27811
3D View Gallery
Deposition: 08/08/2022
Map released: 30/08/2023
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae
Sample: cytoplasmic dynein(E2448Q) bound to Lis1 in chi conformation
Fitted models: 8e00

Deposition Authors: Reimer JM, Lahiri I, Leschziner AE
Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Karasmanis EP , Reimer JM, Kendrick AA , Nguyen KHV, Rodriguez JA, Truong JB , Lahiri I, Reck-Peterson SL , Leschziner AE
(2023) Nat Struct Mol Biol , 30 , 1357 - 1364
PUBMED: 37620585
DOI: doi:10.1038/s41594-023-01069-6
ISSN: 1545-9985